Multisite Phosphorylation of NuMA-Related LIN-5 Controls Mitotic Spindle Positioning in C. elegans

During cell division, the mitotic spindle segregates replicated chromosomes to opposite poles of the cell, while the position of the spindle determines the plane of cleavage. Spindle positioning and chromosome segregation depend on pulling forces on microtubules extending from the centrosomes to the...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Portegijs, Vincent, Fielmich, Lars-Eric, Galli, Matilde, Schmidt, Ruben, Muñoz, Javier, van Mourik, Tim, Akhmanova, Anna, Heck, Albert J. R., Boxem, Mike, van den Heuvel, Sander
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053539/
https://ncbi.nlm.nih.gov/pubmed/27711157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006291
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