Keratin 13 Is Enriched in Prostate Tubule-Initiating Cells and May Identify Primary Prostate Tumors that Metastasize to the Bone

BACKGROUND: Benign human prostate tubule-initiating cells (TIC) and aggressive prostate cancer display common traits, including tolerance of low androgen levels, resistance to apoptosis, and microenvironment interactions that drive epithelial budding and outgrowth. TIC can be distinguished from epit...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Sandy, Cadaneanu, Radu M., Zhang, Baohui, Huo, Lihong, Lai, Kevin, Li, Xinmin, Galet, Colette, Grogan, Tristan R., Elashoff, David, Freedland, Stephen J., Rettig, Matthew, Aronson, William J., Knudsen, Beatrice S., Lewis, Michael S., Garraway, Isla P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053503/
https://ncbi.nlm.nih.gov/pubmed/27711225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163232
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