Keratin 13 Is Enriched in Prostate Tubule-Initiating Cells and May Identify Primary Prostate Tumors that Metastasize to the Bone

BACKGROUND: Benign human prostate tubule-initiating cells (TIC) and aggressive prostate cancer display common traits, including tolerance of low androgen levels, resistance to apoptosis, and microenvironment interactions that drive epithelial budding and outgrowth. TIC can be distinguished from epit...

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Udgivet i:PLoS One
Main Authors: Liu, Sandy, Cadaneanu, Radu M., Zhang, Baohui, Huo, Lihong, Lai, Kevin, Li, Xinmin, Galet, Colette, Grogan, Tristan R., Elashoff, David, Freedland, Stephen J., Rettig, Matthew, Aronson, William J., Knudsen, Beatrice S., Lewis, Michael S., Garraway, Isla P.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053503/
https://ncbi.nlm.nih.gov/pubmed/27711225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163232
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