Keratin 13 Is Enriched in Prostate Tubule-Initiating Cells and May Identify Primary Prostate Tumors that Metastasize to the Bone

BACKGROUND: Benign human prostate tubule-initiating cells (TIC) and aggressive prostate cancer display common traits, including tolerance of low androgen levels, resistance to apoptosis, and microenvironment interactions that drive epithelial budding and outgrowth. TIC can be distinguished from epit...

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Veröffentlicht in:PLoS One
Hauptverfasser: Liu, Sandy, Cadaneanu, Radu M., Zhang, Baohui, Huo, Lihong, Lai, Kevin, Li, Xinmin, Galet, Colette, Grogan, Tristan R., Elashoff, David, Freedland, Stephen J., Rettig, Matthew, Aronson, William J., Knudsen, Beatrice S., Lewis, Michael S., Garraway, Isla P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053503/
https://ncbi.nlm.nih.gov/pubmed/27711225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163232
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