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Chromosomal instability in untreated primary prostate cancer as an indicator of metastatic potential

BACKGROUND: Metastatic prostate cancer (PC) is highly lethal. The ability to identify primary tumors capable of dissemination is an unmet need in the quest to understand lethal biology and improve patient outcomes. Previous studies have linked chromosomal instability (CIN), which generates aneuploid...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Miller, Eric T., You, Sungyong, Cadaneanu, Radu M., Kim, Minhyung, Yoon, Junhee, Liu, Sandy T., Li, Xinmin, Kwan, Lorna, Hodge, Jennelle, Quist, Michael J., Grasso, Catherine S., Lewis, Michael S., Knudsen, Beatrice S., Freeman, Michael R., Garraway, Isla P.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7204307/
https://ncbi.nlm.nih.gov/pubmed/32380981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06817-1
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