Chromosomal instability in untreated primary prostate cancer as an indicator of metastatic potential

BACKGROUND: Metastatic prostate cancer (PC) is highly lethal. The ability to identify primary tumors capable of dissemination is an unmet need in the quest to understand lethal biology and improve patient outcomes. Previous studies have linked chromosomal instability (CIN), which generates aneuploid...

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Udgivet i:BMC Cancer
Main Authors: Miller, Eric T., You, Sungyong, Cadaneanu, Radu M., Kim, Minhyung, Yoon, Junhee, Liu, Sandy T., Li, Xinmin, Kwan, Lorna, Hodge, Jennelle, Quist, Michael J., Grasso, Catherine S., Lewis, Michael S., Knudsen, Beatrice S., Freeman, Michael R., Garraway, Isla P.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7204307/
https://ncbi.nlm.nih.gov/pubmed/32380981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06817-1
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