Chromosomal instability in untreated primary prostate cancer as an indicator of metastatic potential

BACKGROUND: Metastatic prostate cancer (PC) is highly lethal. The ability to identify primary tumors capable of dissemination is an unmet need in the quest to understand lethal biology and improve patient outcomes. Previous studies have linked chromosomal instability (CIN), which generates aneuploid...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Miller, Eric T., You, Sungyong, Cadaneanu, Radu M., Kim, Minhyung, Yoon, Junhee, Liu, Sandy T., Li, Xinmin, Kwan, Lorna, Hodge, Jennelle, Quist, Michael J., Grasso, Catherine S., Lewis, Michael S., Knudsen, Beatrice S., Freeman, Michael R., Garraway, Isla P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7204307/
https://ncbi.nlm.nih.gov/pubmed/32380981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06817-1
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