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Keratin 13 Is Enriched in Prostate Tubule-Initiating Cells and May Identify Primary Prostate Tumors that Metastasize to the Bone

BACKGROUND: Benign human prostate tubule-initiating cells (TIC) and aggressive prostate cancer display common traits, including tolerance of low androgen levels, resistance to apoptosis, and microenvironment interactions that drive epithelial budding and outgrowth. TIC can be distinguished from epit...

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發表在:PLoS One
Main Authors: Liu, Sandy, Cadaneanu, Radu M., Zhang, Baohui, Huo, Lihong, Lai, Kevin, Li, Xinmin, Galet, Colette, Grogan, Tristan R., Elashoff, David, Freedland, Stephen J., Rettig, Matthew, Aronson, William J., Knudsen, Beatrice S., Lewis, Michael S., Garraway, Isla P.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053503/
https://ncbi.nlm.nih.gov/pubmed/27711225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163232
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