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Review: Modulating the unfolded protein response to prevent neurodegeneration and enhance memory
Recent evidence has placed the unfolded protein response (UPR) at the centre of pathological processes leading to neurodegenerative disease. The translational repression caused by UPR activation starves neurons of the essential proteins they need to function and survive. Restoration of protein synth...
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| Veröffentlicht in: | Neuropathol Appl Neurobiol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5053297/ https://ncbi.nlm.nih.gov/pubmed/25556298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nan.12211 |
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