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Review: Modulating the unfolded protein response to prevent neurodegeneration and enhance memory

Recent evidence has placed the unfolded protein response (UPR) at the centre of pathological processes leading to neurodegenerative disease. The translational repression caused by UPR activation starves neurons of the essential proteins they need to function and survive. Restoration of protein synth...

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Détails bibliographiques
Publié dans:Neuropathol Appl Neurobiol
Auteurs principaux: Halliday, Mark, Mallucci, Giovanna R.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053297/
https://ncbi.nlm.nih.gov/pubmed/25556298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nan.12211
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