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The unfolded protein response: mechanisms and therapy of neurodegeneration

Activation of the unfolded protein response is emerging as a common theme in protein-misfolding neurodegenerative diseases, with relevant markers observed in patient tissue and mouse models. Genetic and pharmacological manipulation of the pathway in several mouse models has shown that this is not a...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Smith, Heather L., Mallucci, Giovanna R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958893/
https://ncbi.nlm.nih.gov/pubmed/27190028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aww101
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