Marked replicative advantage of human mtDNA carrying a point mutation that causes the MELAS encephalomyopathy.

Ítems similars

• MELAS mutation in mtDNA binding site for transcription termination factor causes defects in protein synthesis and in respiration but no change in levels of upstream and downstream mature transcripts.
  per: Chomyn, A, et al.
  Publicat: (1992)
• The mutation rate of the human mtDNA deletion mtDNA4977.
  per: Shenkar, R., et al.
  Publicat: (1996)
• RNASEH1 Mutations Impair mtDNA Replication and Cause Adult-Onset Mitochondrial Encephalomyopathy
  per: Reyes, Aurelio, et al.
  Publicat: (2015)
• Fine mapping of mitochondrial RNAs derived from the mtDNA region containing a point mutation associated with MELAS.
  per: Koga, Y, et al.
  Publicat: (1993)
• Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations
  per: Chen, Hsiuchen, et al.
  Publicat: (2010)