MELAS mutation in mtDNA binding site for transcription termination factor causes defects in protein synthesis and in respiration but no change in levels of upstream and downstream mature transcripts.

Lignende værker

• Marked replicative advantage of human mtDNA carrying a point mutation that causes the MELAS encephalomyopathy.
  af: Yoneda, M, et al.
  Udgivet: (1992)
• The mutation rate of the human mtDNA deletion mtDNA4977.
  af: Shenkar, R., et al.
  Udgivet: (1996)
• Ancient mtDNA Genetic Variants Modulate mtDNA Transcription and Replication
  af: Suissa, Sarit, et al.
  Udgivet: (2009)
• Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations
  af: Chen, Hsiuchen, et al.
  Udgivet: (2010)
• MELAS and Kearns–Sayre overlap syndrome due to the mtDNA m. A3243G mutation and large-scale mtDNA deletions
  af: Yu, Nian, et al.
  Udgivet: (2016)