Broadly Neutralizing Hemagglutinin Stalk-Specific Antibodies Induce Potent Phagocytosis of Immune Complexes by Neutrophils in an Fc-Dependent Manner

Broadly neutralizing antibodies that recognize the conserved hemagglutinin (HA) stalk have emerged as exciting new biotherapeutic tools to combat seasonal and pandemic influenza viruses. Our general understanding of the mechanisms by which stalk-specific antibodies achieve protection is rapidly evol...

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Publicado en:mBio
Autores principales: Mullarkey, Caitlin E., Bailey, Mark J., Golubeva, Diana A., Tan, Gene S., Nachbagauer, Raffael, He, Wenqian, Novakowski, Kyle E., Bowdish, Dawn M., Miller, Matthew S., Palese, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050345/
https://ncbi.nlm.nih.gov/pubmed/27703076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01624-16
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