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The challenge of developing autophagy inhibition as a therapeutic strategy

The finding that cancer chemotherapeutic drugs and ionizing radiation often promote autophagy has provided the foundation for clinical trials combining autophagy-blocking agents with antitumor drugs and radiation. The premise driving these trials is that therapy-induced autophagy is cytoprotective;...

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Bibliografiske detaljer
Udgivet i:Cancer Res
Hovedforfatter: Gewirtz, David A.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050139/
https://ncbi.nlm.nih.gov/pubmed/27634767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-0722
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