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Autophagy Inhibition for Chemosensitization and Radiosensitization in Cancer: Do the Preclinical Data Support This Therapeutic Strategy?

Recognition of the cytoprotective functions of autophagy that occur in tumor cells exposed to various forms of chemotherapy or radiation has generated intense interest in the possibility that pharmacological interference with autophagy could provide a clinical strategy for overcoming therapeutic res...

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Detalhes bibliográficos
Main Authors: Bristol, Molly L., Emery, Sean M., Maycotte, Paola, Thorburn, Andrew, Chakradeo, Shweta, Gewirtz, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583507/
https://ncbi.nlm.nih.gov/pubmed/23291713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.199802
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