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The Switch between Protective and Nonprotective Autophagy; Implications for Autophagy Inhibition as a Therapeutic Strategy in Cancer

Autophagy, a process of cellular self-degradation and cell survival whereby the cell generates energy and metabolic intermediates under conditions of stress (i.e., nutrient deprivation), is also commonly induced in tumor cells in response to chemotherapy and radiation. While chemotherapy-induced aut...

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Detalhes bibliográficos
Publicado no:Biology (Basel)
Autor principal: Gewirtz, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7168293/
https://ncbi.nlm.nih.gov/pubmed/31947952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology9010012
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