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Autophagy is not uniformly cytoprotective: a personalized medicine approach for autophagy inhibition as a therapeutic strategy in non-small cell lung cancer

BACKGROUND: Lung cancer is the leading cause of cancer-related death worldwide. In addition to surgical resection, which is considered first-line treatment at early stages of the disease, chemotherapy and radiation are widely used when the disease is advanced. Of multiple responses that may occur in...

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Vydáno v:Biochim Biophys Acta
Hlavní autoři: Saleh, Tareq, Cuttino, Laurie, Gewirtz, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961553/
https://ncbi.nlm.nih.gov/pubmed/27316314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2016.06.012
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