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Aggregation and Prion-Like Properties of Misfolded Tumor Suppressors: Is Cancer a Prion Disease?

Prion diseases are disorders that share several characteristics that are typical of many neurodegenerative diseases. Recently, several studies have extended the prion concept to pathological aggregation in malignant tumors involving misfolded p53, a tumor-suppressor protein. The aggregation of p53 a...

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Detaylı Bibliyografya
Yayımlandı:Cold Spring Harb Perspect Biol
Asıl Yazarlar: Costa, Danielly C.F., de Oliveira, Guilherme A.P., Cino, Elio A., Soares, Iaci N., Rangel, Luciana P., Silva, Jerson L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5046694/
https://ncbi.nlm.nih.gov/pubmed/27549118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a023614
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