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Misfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer

The current understanding of the molecular mechanisms that lead to cancer is not sufficient to explain the loss or gain of function in proteins related to tumorigenic processes. Among them, more than 100 oncogenes, 20–30 tumor-suppressor genes, and hundreds of genes participating in DNA repair and r...

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Detalles Bibliográficos
Publicado en:Front Oncol
Main Authors: de Oliveira, Guilherme A. P., Rangel, Luciana P., Costa, Danielly C., Silva, Jerson L.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413674/
https://ncbi.nlm.nih.gov/pubmed/25973395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00097
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