Isoniazid metabolism and hepatotoxicity

Isoniazid (INH) is highly effective for the management of tuberculosis. However, it can cause liver injury and even liver failure. INH metabolism has been thought to be associated with INH-induced liver injury. This review summarized the metabolic pathways of INH and discussed their associations wit...

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Bibliografiske detaljer
Udgivet i:Acta Pharm Sin B
Main Authors: Wang, Pengcheng, Pradhan, Komal, Zhong, Xiao-bo, Ma, Xiaochao
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2016
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045547/
https://ncbi.nlm.nih.gov/pubmed/27709007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2016.07.014
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