A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation.

The inward Na+ current underlying the action potential in nerve is terminated by inactivation. The preceding report shows that deletions within the intracellular linker between domains III and IV remove inactivation, but mutation of conserved basic and paired acidic amino acids has little effect. He...

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Hlavní autoři: West, J W, Patton, D E, Scheuer, T, Wang, Y, Goldin, A L, Catterall, W A
Médium: Artigo
Jazyk:Inglês
Vydáno: 1992
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC50452/
https://ncbi.nlm.nih.gov/pubmed/1332060
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