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Highly Selective Tau-SPECT Imaging Probes for Detection of Neurofibrillary Tangles in Alzheimer’s Disease

Neurofibrillary tangles composed of aggregates of hyperphosphorylated tau proteins are one of the neuropathological hallmarks of Alzheimer’s disease (AD) in addition to the deposition of β-amyloid plaques. Since the deposition of tau aggregates is closely associated with the severity of AD, the in v...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Ono, Masahiro, Watanabe, Hiroyuki, Kitada, Ayane, Matsumura, Kenji, Ihara, Masafumi, Saji, Hideo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043239/
https://ncbi.nlm.nih.gov/pubmed/27687137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34197
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