(18)F-Labeled Phenyldiazenyl Benzothiazole for in Vivo Imaging of Neurofibrillary Tangles in Alzheimer's Disease Brains

[Image: see text] We synthesized and evaluated (E)-4-((6-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)benzo[d]thiazol-2-yl)diazenyl)-N,N-dimethylaniline (FPPDB) as a probe for the imaging of neurofibrillary tangles (NFTs) in patients with Alzheimer's disease (AD). In assays using thioflavin S (ThS) as a...

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Detalhes bibliográficos
Main Authors: Matsumura, Kenji, Ono, Masahiro, Kimura, Hiroyuki, Ueda, Masashi, Nakamoto, Yuji, Togashi, Kaori, Okamoto, Yoko, Ihara, Masafumi, Takahashi, Ryosuke, Saji, Hideo
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2011
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025873/
https://ncbi.nlm.nih.gov/pubmed/24900371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200230e
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