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Highly Selective Tau-SPECT Imaging Probes for Detection of Neurofibrillary Tangles in Alzheimer’s Disease

Neurofibrillary tangles composed of aggregates of hyperphosphorylated tau proteins are one of the neuropathological hallmarks of Alzheimer’s disease (AD) in addition to the deposition of β-amyloid plaques. Since the deposition of tau aggregates is closely associated with the severity of AD, the in v...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ono, Masahiro, Watanabe, Hiroyuki, Kitada, Ayane, Matsumura, Kenji, Ihara, Masafumi, Saji, Hideo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043239/
https://ncbi.nlm.nih.gov/pubmed/27687137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34197
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