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Highly Selective Tau-SPECT Imaging Probes for Detection of Neurofibrillary Tangles in Alzheimer’s Disease

Neurofibrillary tangles composed of aggregates of hyperphosphorylated tau proteins are one of the neuropathological hallmarks of Alzheimer’s disease (AD) in addition to the deposition of β-amyloid plaques. Since the deposition of tau aggregates is closely associated with the severity of AD, the in v...

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書目詳細資料
發表在:Sci Rep
Main Authors: Ono, Masahiro, Watanabe, Hiroyuki, Kitada, Ayane, Matsumura, Kenji, Ihara, Masafumi, Saji, Hideo
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043239/
https://ncbi.nlm.nih.gov/pubmed/27687137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34197
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