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Rhodanine and Thiohydantoin Derivatives for Detecting Tau Pathology in Alzheimer’s Brains
[Image: see text] A novel series of rhodanin (RH) and thiohydantoin (TH) derivatives were designed and synthesized for detecting tau pathology in the brains of patients with Alzheimer’s disease (AD). In experiments in vitro using tau and β-amyloid (Aβ) aggregates, the TH derivative, TH2, showed high...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369744/ https://ncbi.nlm.nih.gov/pubmed/22778869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn200002t |
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