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Rhodanine and Thiohydantoin Derivatives for Detecting Tau Pathology in Alzheimer’s Brains

[Image: see text] A novel series of rhodanin (RH) and thiohydantoin (TH) derivatives were designed and synthesized for detecting tau pathology in the brains of patients with Alzheimer’s disease (AD). In experiments in vitro using tau and β-amyloid (Aβ) aggregates, the TH derivative, TH2, showed high...

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Hlavní autoři: Ono, Masahiro, Hayashi, Shun, Matsumura, Kenji, Kimura, Hiroyuki, Okamoto, Yoko, Ihara, Masafumi, Takahashi, Ryosuke, Mori, Hiroshi, Saji, Hideo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2011
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369744/
https://ncbi.nlm.nih.gov/pubmed/22778869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn200002t
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