Development of Novel (123)I-Labeled Pyridyl Benzofuran Derivatives for SPECT Imaging of β-Amyloid Plaques in Alzheimer’s Disease

Imaging of β-amyloid (Aβ) plaques in the brain may facilitate the diagnosis of cerebral β-amyloidosis, risk prediction of Alzheimer’s disease (AD), and effectiveness of anti-amyloid therapies. The purpose of this study was to evaluate novel (123)I-labeled pyridyl benzofuran derivatives as SPECT prob...

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Autors principals: Ono, Masahiro, Cheng, Yan, Kimura, Hiroyuki, Watanabe, Hiroyuki, Matsumura, Kenji, Yoshimura, Masashi, Iikuni, Shimpei, Okamoto, Yoko, Ihara, Masafumi, Takahashi, Ryosuke, Saji, Hideo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772825/
https://ncbi.nlm.nih.gov/pubmed/24058519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074104
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