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DNA shape features improve transcription factor binding site predictions in vivo
Interactions of transcription factors (TFs) with DNA comprise a complex interplay between base-specific amino acid contacts and readout of DNA structure. Recent studies highlighted the complementarity of DNA sequence and shape in modeling TF binding in vitro. Here, we provide a comprehensive evaluat...
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| Veröffentlicht in: | Cell Syst |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5042832/ https://ncbi.nlm.nih.gov/pubmed/27546793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2016.07.001 |
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