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Expanding the repertoire of DNA shape features for genome-scale studies of transcription factor binding

Uncovering the mechanisms that affect the binding specificity of transcription factors (TFs) is critical for understanding the principles of gene regulation. Although sequence-based models have been used successfully to predict TF binding specificities, we found that including DNA shape information...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Li, Jinsen, Sagendorf, Jared M., Chiu, Tsu-Pei, Pasi, Marco, Perez, Alberto, Rohs, Remo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728407/
https://ncbi.nlm.nih.gov/pubmed/29165643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1145
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