Arg126 and Asp49 Are Essential for the Catalytic Function of Microsomal Prostaglandin E(2) Synthase 1 and Ser127 Is Not

INTRODUCTION: Prostaglandins are signaling molecules that regulate different physiological processes, involving allergic and inflammatory responses and cardiovascular control. They are involved in several pathophysiological processes, including inflammation and cancer. The inducible terminal enzyme,...

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Veröffentlicht in:PLoS One
Hauptverfasser: Raouf, Joan, Rafique, Nazmi, Goodman, Michael Christopher, Idborg, Helena, Bergqvist, Filip, Armstrong, Richard N., Jakobsson, Per-Johan, Morgenstern, Ralf, Spahiu, Linda
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042469/
https://ncbi.nlm.nih.gov/pubmed/27684486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163600
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