Arg126 and Asp49 Are Essential for the Catalytic Function of Microsomal Prostaglandin E(2) Synthase 1 and Ser127 Is Not

INTRODUCTION: Prostaglandins are signaling molecules that regulate different physiological processes, involving allergic and inflammatory responses and cardiovascular control. They are involved in several pathophysiological processes, including inflammation and cancer. The inducible terminal enzyme,...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Raouf, Joan, Rafique, Nazmi, Goodman, Michael Christopher, Idborg, Helena, Bergqvist, Filip, Armstrong, Richard N., Jakobsson, Per-Johan, Morgenstern, Ralf, Spahiu, Linda
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042469/
https://ncbi.nlm.nih.gov/pubmed/27684486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163600
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