Arg126 and Asp49 Are Essential for the Catalytic Function of Microsomal Prostaglandin E(2) Synthase 1 and Ser127 Is Not

INTRODUCTION: Prostaglandins are signaling molecules that regulate different physiological processes, involving allergic and inflammatory responses and cardiovascular control. They are involved in several pathophysiological processes, including inflammation and cancer. The inducible terminal enzyme,...

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Udgivet i:PLoS One
Main Authors: Raouf, Joan, Rafique, Nazmi, Goodman, Michael Christopher, Idborg, Helena, Bergqvist, Filip, Armstrong, Richard N., Jakobsson, Per-Johan, Morgenstern, Ralf, Spahiu, Linda
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042469/
https://ncbi.nlm.nih.gov/pubmed/27684486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163600
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