Arg126 and Asp49 Are Essential for the Catalytic Function of Microsomal Prostaglandin E(2) Synthase 1 and Ser127 Is Not

INTRODUCTION: Prostaglandins are signaling molecules that regulate different physiological processes, involving allergic and inflammatory responses and cardiovascular control. They are involved in several pathophysiological processes, including inflammation and cancer. The inducible terminal enzyme,...

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Pubblicato in:PLoS One
Autori principali: Raouf, Joan, Rafique, Nazmi, Goodman, Michael Christopher, Idborg, Helena, Bergqvist, Filip, Armstrong, Richard N., Jakobsson, Per-Johan, Morgenstern, Ralf, Spahiu, Linda
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042469/
https://ncbi.nlm.nih.gov/pubmed/27684486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163600
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