An intrastrand d(GpG) platinum crosslink in duplex M13 DNA is refractory to repair by human cell extracts.

We have examined the ability of human cell extracts to repair the most frequent DNA adduct caused by the cancer chemotherapeutic agent cis-diamminedichloroplatinum(II). A circular DNA duplex with an intrastrand d(GpG) crosslink positioned at a specific site was synthesized. Human cell extracts were...

Celý popis

Podrobná bibliografie

Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Szymkowski, D E, Yarema, K, Essigmann, J M, Lippard, S J, Wood, R D
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1992
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50424/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1438274/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.22.10772
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!