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Genotoxicity of three food processing contaminants in transgenic mice expressing human sulfotransferases 1A1 and 1A2 as assessed by the in vivo alkaline single cell gel electrophoresis assay

The food processing contaminants 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP), 5‐hydroxymethylfurfural (HMF) and 2,5 dimethylfuran (DMF) are potentially both mutagenic and carcinogenic in vitro and/or in vivo, although data on DMF is lacking. The PHIP metabolite N‐hydroxy‐PhIP and HMF are...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Environ Mol Mutagen
मुख्य लेखकों: Høie, Anja Hortemo, Svendsen, Camilla, Brunborg, Gunnar, Glatt, Hansruedi, Alexander, Jan, Meinl, Walter, Husøy, Trine
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042101/
https://ncbi.nlm.nih.gov/pubmed/26270892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.21963
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