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Genotoxicity of three food processing contaminants in transgenic mice expressing human sulfotransferases 1A1 and 1A2 as assessed by the in vivo alkaline single cell gel electrophoresis assay

The food processing contaminants 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP), 5‐hydroxymethylfurfural (HMF) and 2,5 dimethylfuran (DMF) are potentially both mutagenic and carcinogenic in vitro and/or in vivo, although data on DMF is lacking. The PHIP metabolite N‐hydroxy‐PhIP and HMF are...

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Detalhes bibliográficos
Publicado no:Environ Mol Mutagen
Main Authors: Høie, Anja Hortemo, Svendsen, Camilla, Brunborg, Gunnar, Glatt, Hansruedi, Alexander, Jan, Meinl, Walter, Husøy, Trine
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042101/
https://ncbi.nlm.nih.gov/pubmed/26270892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.21963
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