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An in vitro study on the genotoxic effect of substituted furans in cells transfected with human metabolizing enzymes: 2,5-dimethylfuran and furfuryl alcohol

2,5-Dimethylfuran (DMF) and furfuryl alcohol (FFA) are two substituted furans that are formed during the processing of foods and have also been used as food flavorings. DMF and FFA are proposed to be bioactivated by human sulfotransferases (SULTs) which are not expressed in conventional cell lines u...

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Détails bibliographiques
Publié dans:Mutagenesis
Auteurs principaux: Huffman, Minor P., Høie, Anja H., Svendsen, Camilla, Brunborg, Gunnar, Murkovic, Michael, Glatt, Hansruedi, Husøy, Trine
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992344/
https://ncbi.nlm.nih.gov/pubmed/27226491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/gew025
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