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Furan Carcinogenicity: DNA binding and genotoxicity of furan in rats in vivo

SCOPE: Furan is a potent hepatotoxicant and liver carcinogen in rodents. However, short-term tests for genotoxicity of furan are inconclusive. The aim of this study was to assess the potential of furan to covalently bind to DNA, and to assess furan genotoxicity in rats in vivo. MATERIALS AND METHODS...

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Detalhes bibliográficos
Main Authors: Neuwirth, Carolin, Mosesso, Pasquale, Pepe, Gaetano, Fiore, Mario, Malfatti, Mike, Turteltaub, Ken, Dekant, Wolfgang, Mally, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892142/
https://ncbi.nlm.nih.gov/pubmed/22865590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201200226
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