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Furan Carcinogenicity: DNA binding and genotoxicity of furan in rats in vivo

SCOPE: Furan is a potent hepatotoxicant and liver carcinogen in rodents. However, short-term tests for genotoxicity of furan are inconclusive. The aim of this study was to assess the potential of furan to covalently bind to DNA, and to assess furan genotoxicity in rats in vivo. MATERIALS AND METHODS...

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Hlavní autoři: Neuwirth, Carolin, Mosesso, Pasquale, Pepe, Gaetano, Fiore, Mario, Malfatti, Mike, Turteltaub, Ken, Dekant, Wolfgang, Mally, Angela
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892142/
https://ncbi.nlm.nih.gov/pubmed/22865590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201200226
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