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mTOR regulates proteasomal degradation and Dp1/E2F1- mediated transcription of KPNA2 in lung cancer cells

Karyopherin subunit alpha-2 (KPNA2) is overexpressed in various human cancers and is associated with cancer invasiveness and poor prognosis in patient. Nevertheless, the regulation of KPNA2 expression in cancers remains unclear. We herein applied epidermal growth factor (EGF) and five EGF receptor (...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Wang, Chun-I, Chen, Yan-Yu, Wang, Chih-Liang, Yu, Jau-Song, Chang, Yu-Sun, Yu, Chia-Jung
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041915/
https://ncbi.nlm.nih.gov/pubmed/27009856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8170
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