mTOR Complex 2 Targets Akt for Proteasomal Degradation via Phosphorylation at the Hydrophobic Motif

Lignende værker

• Akt Phosphorylates Wnt Coactivator and Chromatin Effector Pygo2 at Serine 48 to Antagonize Its Ubiquitin/Proteasome-mediated Degradation
  af: Li, Qiuling, et al.
  Udgivet: (2015)
• Disruption of the Interface between the Pleckstrin Homology (PH) and Kinase Domains of Akt Protein Is Sufficient for Hydrophobic Motif Site Phosphorylation in the Absence of mTORC2
  af: Warfel, Noel A., et al.
  Udgivet: (2011)
• Expression of phosphorylated Akt/mTOR and clinical significance in human ameloblastoma
  af: Li, Ning, et al.
  Udgivet: (2015)
• Identification of mechanically regulated phosphorylation sites on tuberin (TSC2) that control mechanistic target of rapamycin (mTOR) signaling
  af: Jacobs, Brittany L., et al.
  Udgivet: (2017)
• Small molecule H89 renders the phosphorylation of S6K1 and AKT resistant to mTOR inhibitors
  af: Melick, Chase H., et al.
  Udgivet: (2020)