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IRF1 Negatively Regulates Oncogenic KPNA2 Expression Under Growth Stimulation and Hypoxia in Lung Cancer Cells

PURPOSE: Karyopherin alpha 2 (KPNA2) has been reported as an oncogenic protein in numerous human cancers and is currently considered a potential therapeutic target. However, the transcriptional regulation and physiological conditions underlying KPNA2 expression remain unclear. The aim of the present...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Huang, Jie-Xin, Wu, Yi-Cheng, Cheng, Ya-Yun, Wang, Chih-Liang, Yu, Chia-Jung
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939401/
https://ncbi.nlm.nih.gov/pubmed/31920336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S221832
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