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mTOR regulates proteasomal degradation and Dp1/E2F1- mediated transcription of KPNA2 in lung cancer cells

Karyopherin subunit alpha-2 (KPNA2) is overexpressed in various human cancers and is associated with cancer invasiveness and poor prognosis in patient. Nevertheless, the regulation of KPNA2 expression in cancers remains unclear. We herein applied epidermal growth factor (EGF) and five EGF receptor (...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Chun-I, Chen, Yan-Yu, Wang, Chih-Liang, Yu, Jau-Song, Chang, Yu-Sun, Yu, Chia-Jung
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041915/
https://ncbi.nlm.nih.gov/pubmed/27009856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8170
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