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A single molecule assay to probe monovalent and multivalent bonds between hyaluronan and its key leukocyte receptor CD44 under force

Glycosaminoglycans (GAGs), a category of linear, anionic polysaccharides, are ubiquitous in the extracellular space, and important extrinsic regulators of cell function. Despite the recognized significance of mechanical stimuli in cellular communication, however, only few single molecule methods are...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Bano, Fouzia, Banerji, Suneale, Howarth, Mark, Jackson, David G., Richter, Ralf P.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040960/
https://ncbi.nlm.nih.gov/pubmed/27679982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34176
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