Analysis of CD44-Hyaluronan Interactions in an Artificial Membrane System: INSIGHTS INTO THE DISTINCT BINDING PROPERTIES OF HIGH AND LOW MOLECULAR WEIGHT HYALURONAN

CD44 is a major cell surface receptor for the large polydisperse glycosaminoglycan hyaluronan (HA). Binding of the long and flexible HA chains is thought to be stabilized by the multivalent nature of the sugar molecule. In addition, high and low molecular weight forms of HA provoke distinct proinfla...

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Detalhes bibliográficos
Main Authors: Wolny, Patricia M., Banerji, Suneale, Gounou, Céline, Brisson, Alain R., Day, Anthony J., Jackson, David G., Richter, Ralf P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943326/
https://ncbi.nlm.nih.gov/pubmed/20663884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.137562
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