The Inflammation-associated Protein TSG-6 Cross-links Hyaluronan via Hyaluronan-induced TSG-6 Oligomers

Tumor necrosis factor-stimulated gene-6 (TSG-6) is a hyaluronan (HA)-binding protein that plays important roles in inflammation and ovulation. TSG-6-mediated cross-linking of HA has been proposed as a functional mechanism (e.g. for regulating leukocyte adhesion), but direct evidence for cross-linkin...

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Bibliographische Detailangaben
Hauptverfasser: Baranova, Natalia S., Nilebäck, Erik, Haller, F. Michael, Briggs, David C., Svedhem, Sofia, Day, Anthony J., Richter, Ralf P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Glycobiology and Extracellular Matrices
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138277/
https://ncbi.nlm.nih.gov/pubmed/21596748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.247395
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