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Metal Ion-dependent Heavy Chain Transfer Activity of TSG-6 Mediates Assembly of the Cumulus-Oocyte Matrix

The matrix polysaccharide hyaluronan (HA) has a critical role in the expansion of the cumulus cell-oocyte complex (COC), a process that is necessary for ovulation and fertilization in most mammals. Hyaluronan is organized into a cross-linked network by the cooperative action of three proteins, inter...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Briggs, David C., Birchenough, Holly L., Ali, Tariq, Rugg, Marilyn S., Waltho, Jon P., Ievoli, Elena, Jowitt, Thomas A., Enghild, Jan J., Richter, Ralf P., Salustri, Antonietta, Milner, Caroline M., Day, Anthony J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661386/
https://ncbi.nlm.nih.gov/pubmed/26468290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.669838
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