Inter-α-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation

Inter-α-inhibitor is a proteoglycan essential for mammalian reproduction and also plays a less well-characterized role in inflammation. It comprises two homologous “heavy chains” (HC1 and HC2) covalently attached to chondroitin sulfate on the bikunin core protein. Before ovulation, HCs are transferr...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Biol Chem
Main Authors: Briggs, David C., Langford-Smith, Alexander W. W., Birchenough, Holly L., Jowitt, Thomas A., Kielty, Cay M., Enghild, Jan J., Baldock, Clair, Milner, Caroline M., Day, Anthony J.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2020
נושאים:
Glycobiology and Extracellular Matrices
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7170535/
https://ncbi.nlm.nih.gov/pubmed/32144206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011916
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