Inter-α-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation

Inter-α-inhibitor is a proteoglycan essential for mammalian reproduction and also plays a less well-characterized role in inflammation. It comprises two homologous “heavy chains” (HC1 and HC2) covalently attached to chondroitin sulfate on the bikunin core protein. Before ovulation, HCs are transferr...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Briggs, David C., Langford-Smith, Alexander W. W., Birchenough, Holly L., Jowitt, Thomas A., Kielty, Cay M., Enghild, Jan J., Baldock, Clair, Milner, Caroline M., Day, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7170535/
https://ncbi.nlm.nih.gov/pubmed/32144206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011916
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