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Analysis of CD44-Hyaluronan Interactions in an Artificial Membrane System: INSIGHTS INTO THE DISTINCT BINDING PROPERTIES OF HIGH AND LOW MOLECULAR WEIGHT HYALURONAN

CD44 is a major cell surface receptor for the large polydisperse glycosaminoglycan hyaluronan (HA). Binding of the long and flexible HA chains is thought to be stabilized by the multivalent nature of the sugar molecule. In addition, high and low molecular weight forms of HA provoke distinct proinfla...

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Autors principals: Wolny, Patricia M., Banerji, Suneale, Gounou, Céline, Brisson, Alain R., Day, Anthony J., Jackson, David G., Richter, Ralf P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943326/
https://ncbi.nlm.nih.gov/pubmed/20663884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.137562
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