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The High and Low Molecular Weight Forms of Hyaluronan Have Distinct Effects on CD44 Clustering

CD44 is a major cell surface receptor for the glycosaminoglycan hyaluronan (HA). Native high molecular weight hyaluronan (nHA) and oligosaccharides of hyaluronan (oHA) provoke distinct biological effects upon binding to CD44. Despite the importance of such interactions, however, the feature of bindi...

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Detalhes bibliográficos
Main Authors: Yang, Cuixia, Cao, Manlin, Liu, Hua, He, Yiqing, Xu, Jing, Du, Yan, Liu, Yiwen, Wang, Wenjuan, Cui, Lian, Hu, Jiajie, Gao, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522304/
https://ncbi.nlm.nih.gov/pubmed/23118219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.349209
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