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Dendritic cell entry to lymphatic capillaries is orchestrated by CD44 and the hyaluronan glycocalyx

DCs play a vital role in immunity by conveying antigens from peripheral tissues to draining lymph nodes, through afferent lymphatic vessels. Critical to the process is initial docking to the lymphatic endothelial receptor LYVE-1 via its ligand hyaluronan on the DC surface. How this relatively weak b...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: Johnson, Louise A, Banerji, Suneale, Lagerholm, B Christoffer, Jackson, David G
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8008951/
https://ncbi.nlm.nih.gov/pubmed/33687996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000908
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