Synergistic anti-leukemic interactions between ABT-199 and panobinostat in acute myeloid leukemia ex vivo

Cure rates for acute myeloid leukemia (AML) remain suboptimal; thus new treatment strategies are needed for this deadly disease. Poor clinical outcomes have been associated with overexpression of the anti-apoptotic Bcl-2 family proteins Bcl-2, Bcl-xL, and Mcl-1, which have garnered great interest as...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Transl Res
Prif Awduron: Schwartz, Jonathan, Niu, Xiaojia, Walton, Eric, Hurley, Laura, Lin, Hai, Edwards, Holly, Taub, Jeffrey W, Wang, Zhihong, Ge, Yubin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: e-Century Publishing Corporation 2016
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040686/
https://ncbi.nlm.nih.gov/pubmed/27725868
Tagiau: Ychwanegu Tag
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