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Network-based inference of protein activity helps functionalize the genetic landscape of cancer
Identifying the multiple dysregulated oncoproteins that contribute to tumorigenesis in a given patient is crucial for developing personalized treatment plans. However, accurate inference of aberrant protein activity in biological samples is still challenging as genetic alterations are only partially...
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| Publicado en: | Nat Genet |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5040167/ https://ncbi.nlm.nih.gov/pubmed/27322546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3593 |
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